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T-Sapphire

T-Sapphire (Ex-Max 399 nm/Em-Max 511 nm)

T-Sapphire is a weakly dimeric fluorescent protein with a long Stokes' Shift in that it has an excitation peak at 399 nm and an emission peak at 511 nm. It was originally derived from the jellyfish, Aequorea victoria.

Excitation & emission spectra

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Key facts

Excitation maximum
399 nm
Emission maximum
511 nm
Optimal laser line
405
Optimal filter
515/30
Extinction coefficient
44000
Quantum yield
0.6
Molecular weight
26900

T-Sapphire has an excitation maximum at 399 nm and an emission maximum at 511 nm, a Stokes shift of 112 nm. Its extinction coefficient is 44000 M⁻¹cm⁻¹. It is optimally excited by the 405 laser line.

Frequently asked questions

What is T-Sapphire?
T-Sapphire is a weakly dimeric fluorescent protein with a long Stokes' Shift in that it has an excitation peak at 399 nm and an emission peak at 511 nm. It was originally derived from the jellyfish, Aequorea victoria.
What laser excites T-Sapphire?
T-Sapphire is optimally excited by the 405 laser line. Its excitation maximum is 399 nm.
What filter should I use to detect T-Sapphire?
A 515/30 filter captures the peak of the T-Sapphire emission near 511 nm with minimal spillover.