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SiRA 2

SiRA 2 has an excitation peak at 649 nm and an emission peak at 662 nm. SiRA 2 (silicon rhodamine 2) is a near-infrared (NIR) fluorogen for SiRA light-up aptamer. SiRA 2 enables imaging of single RNA in living cells. SiRA 2 is extremely bright, photostable and allows the visualization of mRNA expression in bacteria in no-wash, quencher-free, live-cell imaging experiments. Cell permeable.

Excitation & emission spectra

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Key facts

Excitation maximum
649 nm
Emission maximum
662 nm
Optimal laser line
640
Extinction coefficient
86000
Quantum yield
0.98
Molecular weight
602.81

SiRA 2 has an excitation maximum at 649 nm and an emission maximum at 662 nm, a Stokes shift of 13 nm. Its extinction coefficient is 86000 M⁻¹cm⁻¹. It is optimally excited by the 640 laser line.

Frequently asked questions

What is SiRA 2?
SiRA 2 has an excitation peak at 649 nm and an emission peak at 662 nm. SiRA 2 (silicon rhodamine 2) is a near-infrared (NIR) fluorogen for SiRA light-up aptamer. SiRA 2 enables imaging of single RNA in living cells. SiRA 2 is extremely bright, photostable and allows the visualization of mRNA expression in bacteria in no-wash, quencher-free, live-cell imaging experiments. Cell permeable.
What laser excites SiRA 2?
SiRA 2 is optimally excited by the 640 laser line. Its excitation maximum is 649 nm.