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CypHer5E

CypHer5E (Ex-Max 647 nm/Em-Max 667 nm)

CypHer5E is a pH-sensitive cyanine dye derivative used for reporting cell surface internalization into acidic endosomes. It has an excitation peak at 647 nm and emission peak at 667 nm.

Excitation & emission spectra

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Key facts

Excitation maximum
647 nm
Emission maximum
667 nm
Optimal laser line
628-640
Optimal filter
660/20

CypHer5E has an excitation maximum at 647 nm and an emission maximum at 667 nm, a Stokes shift of 20 nm. It is optimally excited by the 628-640 laser line.

Frequently asked questions

What is CypHer5E?
CypHer5E is a pH-sensitive cyanine dye derivative used for reporting cell surface internalization into acidic endosomes. It has an excitation peak at 647 nm and emission peak at 667 nm.
What laser excites CypHer5E?
CypHer5E is optimally excited by the 628-640 laser line. Its excitation maximum is 647 nm.
What filter should I use to detect CypHer5E?
A 660/20 filter captures the peak of the CypHer5E emission near 667 nm with minimal spillover.