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10-Acetyl-37-dihydroxyphenoxazin

10-Acetyl-37-dihydroxyphenoxazin (Ex-Max 571 nm/Em-Max 584 nm)

10-Acetyl-37-dihydroxyphenoxazin (Amplex Red) is a fluorogenic substrate that is stoichiometrically converted in the presense horseradish peroxidase (HRP) and H2O2. This reagent is commonly used in Microplate Assay or to detect an HRP cojugated antibody.

Excitation & emission spectra

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Key facts

Excitation maximum
571 nm
Emission maximum
584 nm
Optimal laser line
561
Optimal filter
586/14
Extinction coefficient
54000
Molecular weight
257

10-Acetyl-37-dihydroxyphenoxazin has an excitation maximum at 571 nm and an emission maximum at 584 nm, a Stokes shift of 13 nm. Its extinction coefficient is 54000 M⁻¹cm⁻¹. It is optimally excited by the 561 laser line.

Frequently asked questions

What is 10-Acetyl-37-dihydroxyphenoxazin?
10-Acetyl-37-dihydroxyphenoxazin (Amplex Red) is a fluorogenic substrate that is stoichiometrically converted in the presense horseradish peroxidase (HRP) and H2O2. This reagent is commonly used in Microplate Assay or to detect an HRP cojugated antibody.
What laser excites 10-Acetyl-37-dihydroxyphenoxazin?
10-Acetyl-37-dihydroxyphenoxazin is optimally excited by the 561 laser line. Its excitation maximum is 571 nm.
What filter should I use to detect 10-Acetyl-37-dihydroxyphenoxazin?
A 586/14 filter captures the peak of the 10-Acetyl-37-dihydroxyphenoxazin emission near 584 nm with minimal spillover.