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Janelia Fluor 669

Janelia Fluor® 669 (Ex-Max 669 nm/Em-Max 682 nm)

Janelia Fluor® 669 was developed at the Janelia Campus of the Howard Hughes Medical Institute but is commercialized by other vendors. The Janelia Fluor®s family is unique in that the fluorophores are cell-permeable and are available in photoactivatable forms. These fluorophores were developed for super-resolution microscopy (STED, PALM and STORM) and live-cell microscopy in the HaloTag and SNAP-tag versions. Janelia Fluor® 669 has an excitation peak at 669 nm and an emission peak at 682 nm.

Excitation & emission spectra

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Key facts

Excitation maximum
669 nm
Emission maximum
682 nm
Optimal laser line
628-640
Optimal filter
695/40
Relative brightness
3 of 5
Extinction coefficient
116000
Quantum yield
0.37

Janelia Fluor 669 has an excitation maximum at 669 nm and an emission maximum at 682 nm, a Stokes shift of 13 nm. Its extinction coefficient is 116000 M⁻¹cm⁻¹. It is optimally excited by the 628-640 laser line.

Frequently asked questions

What is Janelia Fluor 669?
Janelia Fluor® 669 was developed at the Janelia Campus of the Howard Hughes Medical Institute but is commercialized by other vendors. The Janelia Fluor®s family is unique in that the fluorophores are cell-permeable and are available in photoactivatable forms. These fluorophores were developed for super-resolution microscopy (STED, PALM and STORM) and live-cell microscopy in the HaloTag and SNAP-tag versions. Janelia Fluor® 669 has an excitation peak at 669 nm and an emission peak at 682 nm.
What laser excites Janelia Fluor 669?
Janelia Fluor 669 is optimally excited by the 628-640 laser line. Its excitation maximum is 669 nm.
What filter should I use to detect Janelia Fluor 669?
A 695/40 filter captures the peak of the Janelia Fluor 669 emission near 682 nm with minimal spillover.
How bright is Janelia Fluor 669?
Janelia Fluor 669 has a relative brightness of 3 out of 5 (quantum yield 0.37).