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Alexa Fluor 405

Alexa Fluor™ 405 (Ex-Max 401 nm/Em-Max 421 nm)

Alexa Fluor™ 405 (AF405, Alexa 405) has an excitation peak at 401 nm and an emission peak at 421 nm and is similar in size, brightness and application to ABflo 405® (ABclonal) and Cascade Blue® (ThermoFisher Scientific). Alexa 405 is commonly used in flow cytometery and fluorescence microscopy applications.

Excitation & emission spectra

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Key facts

Excitation maximum
401 nm
Emission maximum
421 nm
Optimal laser line
405
Optimal filter
450/50
Relative brightness
2 of 5
Extinction coefficient
34000
Molecular weight
1028
Commercial antibodies
24k from 10 suppliers

Alexa Fluor 405 has an excitation maximum at 401 nm and an emission maximum at 421 nm, a Stokes shift of 20 nm. Its extinction coefficient is 34000 M⁻¹cm⁻¹. It is optimally excited by the 405 laser line.

Frequently asked questions

What is Alexa Fluor 405?
Alexa Fluor™ 405 (AF405, Alexa 405) has an excitation peak at 401 nm and an emission peak at 421 nm and is similar in size, brightness and application to ABflo 405® (ABclonal) and Cascade Blue® (ThermoFisher Scientific). Alexa 405 is commonly used in flow cytometery and fluorescence microscopy applications.
What laser excites Alexa Fluor 405?
Alexa Fluor 405 is optimally excited by the 405 laser line. Its excitation maximum is 401 nm.
What filter should I use to detect Alexa Fluor 405?
A 450/50 filter captures the peak of the Alexa Fluor 405 emission near 421 nm with minimal spillover.
How bright is Alexa Fluor 405?
Alexa Fluor 405 has a relative brightness of 2 out of 5.
How many antibodies are available conjugated to Alexa Fluor 405?
FluoroFinder tracks 23978 commercially available Alexa Fluor 405 conjugates, searchable by target, clone, host and application.