FluoroFinder

	Supplier
	Catalog #:	NBP2-23571FR (View supplier product page)
	Size	100 μl
	Price	$329.00
	Antigen	Vitronectin
	Clone	A18
	Host	Mouse
	Isotype	IgG1 κ
	Conjugate	DyLight 680
	Target Species	Bovine, Equine, Rabbit
	Applications	ELISA, IHC

	Vitronectin	The protein encoded by this gene functions in part as an adhesive glycoprotein. Differential expression of this protein can promote either cell adhesion or migration as it links cells to the extracellular matrix through a variety of ligands. These ligands include integrins, plasminogen activator inhibitor-1, and urokinase plasminogen activator receptor. This secreted protein can be present in the plasma as a monomer or dimer and forms a multimer in the extracellular matrix of several tissues. This protein also inhibits the membrane-damaging effect of the terminal cytolytic complement pathway and binds to several serpin serine protease inhibitors. This protein can also promote extracellular matrix degradation and thus plays a role in tumorigenesis. It is involved in a variety of other biological processes such as the regulation of the coagulation pathway, wound healing, and tissue remodeling. The heparin-binding domain of this protein give it anti-microbial properties. It is also a lipid binding protein that forms a principal component of high density lipoprotein. [provided by RefSeq, Aug 2020]
	DyLight 680	DyLight™ 680 has an excitation peak at 692 nm and an emission peak at 712 nm, and is spectrally similar to Alexa Fluor™ 680 and Cy5.5. DyLight™ 680 is most commonly used in flow cytometery and fluorescence microscopy applications.

	Additional Sources

Vitronectin Monoclonal / DyLight 680 / A18