Rad50 Monoclonal / DyLight 550 / 13B3
Rad50 Monoclonal / DyLight 550 / 13B3
Product Details
| Supplier | ||
|---|---|---|
| Catalog #: | NB100-147R-0.1ml (View supplier product page) | |
| Size | 100 μl | |
| Price | $449.00 | |
| Antigen | Rad50 | |
| Clone | 13B3 | |
| Host | Mouse | |
| Isotype | IgG1 | |
| Conjugate | DyLight 550 | |
| Target Species | Human, Monkey, Mouse, Rat | |
| Applications | WB, IHC, ICC/IF, IHC-P |
About Rad50 and DyLight 550
| Rad50 | The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Rad50, a protein involved in DNA double-strand break repair. This protein forms a complex with MRE11 and NBS1. The protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends. This protein, cooperating with its partners, is important for DNA double-strand break repair, cell cycle checkpoint activation, telomere maintenance, and meiotic recombination. Knockout studies of the mouse homolog suggest this gene is essential for cell growth and viability. Mutations in this gene are the cause of Nijmegen breakage syndrome-like disorder.[provided by RefSeq, Apr 2010] | |
|---|---|---|
| DyLight 550 | DyLight™ 550 has an excitation peak at 562 nm and an emission peak at 576 nm and is spectrally similar to Alexa Fluor™ 546, Alexa Fluor™ 555, Cy3 and TRITC. DyLight™ 550 is most commonly used in flow cytometery and fluorescence microscopy applications. |
Citations
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