PER2 Monoclonal / Janelia Fluor 646 / 5310
PER2 Monoclonal / Janelia Fluor 646 / 5310
Product Details
Supplier | ||
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Catalog #: | NBP2-43729JF646 (View supplier product page) | |
Size | 100 μl | |
Price | $429.00 | |
Antigen | PER2 | |
Clone | 5310 | |
Host | Mouse | |
Isotype | IgG1 | |
Conjugate | Janelia Fluor 646 | |
Target Species | Human | |
Applications | ICC, IF |
About PER2 and Janelia Fluor 646
PER2 | This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene may increase the risk of getting certain cancers and have been linked to sleep disorders. [provided by RefSeq, Jan 2014] | |
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Janelia Fluor 646 | Janelia Fluor® 646 was developed at the Janelia Campus of the Howard Hughes Medical Institute but is commercialized by other vendors. The Janelia Fluor®s family is unique in that the fluorophores are cell-permeable and are available in photoactivatable forms. These fluorophores were developed for super-resolution microscopy (STED, PALM and STORM) and live-cell microscopy in the HaloTag and SNAP-tag versions. Janelia Fluor® 646 has an excitation peak at 646 nm and an emission peak at 664 nm. |