Pancreatic Polypeptide Monoclonal / Janelia Fluor 646 / 1964
Pancreatic Polypeptide Monoclonal / Janelia Fluor 646 / 1964
Product Details
Supplier | ||
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Catalog #: | NBP2-43634JF646 (View supplier product page) | |
Size | 100 μl | |
Price | $429.00 | |
Antigen | Pancreatic Polypeptide | |
Clone | 1964 | |
Host | Mouse | |
Isotype | IgG2a | |
Conjugate | Janelia Fluor 646 | |
Target Species | Human | |
Applications | ICC, IF |
About Pancreatic Polypeptide and Janelia Fluor 646
Pancreatic Polypeptide | This gene encodes a member of the neuropeptide Y (NPY) family of peptides. The encoded 95 aa preproprotein is synthesized in the pancreatic islets of Langerhans and proteolytically processed to generate two peptide products. These products include the active pancreatic hormone of 36 aa and an icosapeptide of unknown function. This hormone acts as a regulator of pancreatic and gastrointestinal functions and may be important in the regulation of food intake. Plasma level of this hormone has been shown to be reduced in conditions associated with increased food intake and elevated in anorexia nervosa. In addition, infusion of this hormone in obese rodents has shown to decrease weight gain. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016] | |
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Janelia Fluor 646 | Janelia Fluor® 646 was developed at the Janelia Campus of the Howard Hughes Medical Institute but is commercialized by other vendors. The Janelia Fluor®s family is unique in that the fluorophores are cell-permeable and are available in photoactivatable forms. These fluorophores were developed for super-resolution microscopy (STED, PALM and STORM) and live-cell microscopy in the HaloTag and SNAP-tag versions. Janelia Fluor® 646 has an excitation peak at 646 nm and an emission peak at 664 nm. |