FluoroFinder

	Supplier
	Catalog #:	NB110-60992JF549 (View supplier product page)
	Size	100 μl
	Price	$429.00
	Antigen	MMP-13
	Clone	MM0019-12E10
	Host	Mouse
	Isotype	IgG1
	Conjugate	Janelia Fluor 549
	Target Species	Human
	Applications	IHC, IHC-P

	MMP-13	This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease cleaves type II collagen more efficiently than types I and III. It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis. Mutations in this gene are associated with metaphyseal anadysplasia. This gene is part of a cluster of MMP genes on chromosome 11. [provided by RefSeq, Jan 2016]
	Janelia Fluor 549	Janelia Fluor® 549 was developed at the Janelia Campus of the Howard Hughes Medical Institute but is commercialized by other vendors. The Janelia Fluor®s family is unique in that the fluorophores are cell-permeable and are available in photoactivatable forms. These fluorophores were developed for super-resolution microscopy (STED, PALM and STORM) and live-cell microscopy in the HaloTag and SNAP-tag versions. Janelia Fluor® 549 has an excitation peak at 549 nm and an emission peak at 571 nm.

	Additional Sources

MMP-13 Monoclonal / Janelia Fluor 549 / MM0019-12E10