FluoroFinder

	Supplier
	Catalog #:	NB110-60991JF646 (View supplier product page)
	Size	100 μl
	Price	$429.00
	Antigen	MMP-12
	Clone	MM0025-7G20
	Host	Mouse
	Isotype	IgG2
	Conjugate	Janelia Fluor 646
	Target Species	Human
	Applications	IHC, IHC-P

	MMP-12	This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease degrades soluble and insoluble elastin. This gene may play a role in aneurysm formation and mutations in this gene are associated with lung function and chronic obstructive pulmonary disease (COPD). This gene is part of a cluster of MMP genes on chromosome 11. [provided by RefSeq, Jan 2016]
	Janelia Fluor 646	Janelia Fluor® 646 was developed at the Janelia Campus of the Howard Hughes Medical Institute but is commercialized by other vendors. The Janelia Fluor®s family is unique in that the fluorophores are cell-permeable and are available in photoactivatable forms. These fluorophores were developed for super-resolution microscopy (STED, PALM and STORM) and live-cell microscopy in the HaloTag and SNAP-tag versions. Janelia Fluor® 646 has an excitation peak at 646 nm and an emission peak at 664 nm.

	Additional Sources

MMP-12 Monoclonal / Janelia Fluor 646 / MM0025-7G20