FluoroFinder

	Supplier
	Catalog #:	NBP2-11942JF646 (View supplier product page)
	Size	100 μl
	Price	$429.00
	Antigen	CD357
	Clone	MM0313-7R12
	Host	Mouse
	Isotype	IgG1
	Conjugate	Janelia Fluor 646
	Target Species	Human
	Applications	FC

	CD357	This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Feb 2011]
	Janelia Fluor 646	Janelia Fluor® 646 was developed at the Janelia Campus of the Howard Hughes Medical Institute but is commercialized by other vendors. The Janelia Fluor®s family is unique in that the fluorophores are cell-permeable and are available in photoactivatable forms. These fluorophores were developed for super-resolution microscopy (STED, PALM and STORM) and live-cell microscopy in the HaloTag and SNAP-tag versions. Janelia Fluor® 646 has an excitation peak at 646 nm and an emission peak at 664 nm.

	Additional Sources

CD357 Monoclonal / Janelia Fluor 646 / MM0313-7R12