FluoroFinder

	Supplier
	Catalog #:	NBP2-12132JF549 (View supplier product page)
	Size	100 μl
	Price	$429.00
	Antigen	CCR6
	Clone	RM0187-25J7
	Host	Rat
	Isotype	IgG2a
	Conjugate	Janelia Fluor 549
	Target Species	Mouse
	Applications	FC, IHC, IHC-P, IHC-Fr

	CCR6	This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq, Jul 2008]
	Janelia Fluor 549	Janelia Fluor® 549 was developed at the Janelia Campus of the Howard Hughes Medical Institute but is commercialized by other vendors. The Janelia Fluor®s family is unique in that the fluorophores are cell-permeable and are available in photoactivatable forms. These fluorophores were developed for super-resolution microscopy (STED, PALM and STORM) and live-cell microscopy in the HaloTag and SNAP-tag versions. Janelia Fluor® 549 has an excitation peak at 549 nm and an emission peak at 571 nm.

	Additional Sources

CCR6 Monoclonal / Janelia Fluor 549 / RM0187-25J7