BID Monoclonal / Janelia Fluor 549 / 4D3
BID Monoclonal / Janelia Fluor 549 / 4D3
Product Details
Supplier | ||
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Catalog #: | NBP1-19049JF549 (View supplier product page) | |
Size | 100 μl | |
Price | $349.00 | |
Antigen | BID | |
Clone | 4D3 | |
Host | Mouse | |
Isotype | IgG1 κ | |
Conjugate | Janelia Fluor 549 | |
Target Species | Human | |
Applications | ICC, IF |
About BID and Janelia Fluor 549
BID | This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2, and thus regulate apoptosis. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found. [provided by RefSeq, Aug 2020] | |
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Janelia Fluor 549 | Janelia Fluor® 549 was developed at the Janelia Campus of the Howard Hughes Medical Institute but is commercialized by other vendors. The Janelia Fluor®s family is unique in that the fluorophores are cell-permeable and are available in photoactivatable forms. These fluorophores were developed for super-resolution microscopy (STED, PALM and STORM) and live-cell microscopy in the HaloTag and SNAP-tag versions. Janelia Fluor® 549 has an excitation peak at 549 nm and an emission peak at 571 nm. |