Complement C2 Monoclonal / DyLight 650 / 200000.0
Complement C2 Monoclonal / DyLight 650 / 200000.0
Product Details
Supplier | ||
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Catalog #: | NBP1-05067C (View supplier product page) | |
Size | 100 μl | |
Price | $399.00 | |
Antigen | Complement C2 | |
Clone | 200000.0 | |
Host | Mouse | |
Isotype | IgG1 κ | |
Conjugate | DyLight 650 | |
Target Species | Human | |
Applications | WB, ELISA | |
Description | Optimal dilution of this antibody should be experimentally determined. |
About Complement C2 and DyLight 650
Complement C2 | Component C2 is a serum glycoprotein that functions as part of the classical pathway of the complement system. Activated C1 cleaves C2 into C2a and C2b. The serine proteinase C2a then combines with complement factor 4b to create the C3 or C5 convertase. Deficiency of C2 has been reported to associated with certain autoimmune diseases and SNPs in this gene have been associated with altered susceptibility to age-related macular degeneration. This gene localizes within the class III region of the MHC on the short arm of chromosome 6. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described in publications but their full-length sequence has not been determined.[provided by RefSeq, Mar 2009] | |
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DyLight 650 | DyLight™ 650 is a red-emitting fluorophore that excited by the 640 nm laser and collected using a 670/30 nm bandpass filter. DyLight™ 650 has an excitation peak at 652 nm and an emission peak at 672 nm, and is spectrally similar to Alexa Fluor™ 647 and Cy5. DyLight™ 650 is most commonly used in flow cytometery and fluorescence microscopy applications. |