Complement Factor B Monoclonal / DyLight 350 / 6G11
Complement Factor B Monoclonal / DyLight 350 / 6G11
Product Details
| Supplier | ||
|---|---|---|
| Catalog #: | NBP1-05129UV (View supplier product page) | |
| Size | 100 μl | |
| Price | $379.00 | |
| Antigen | Complement Factor B | |
| Clone | 6G11 | |
| Host | Mouse | |
| Isotype | IgG1 κ | |
| Conjugate | DyLight 350 | |
| Target Species | Human | |
| Applications | WB, ELISA | |
| Description | Optimal dilution of this antibody should be experimentally determined. |
About Complement Factor B and DyLight 350
| Complement Factor B | This gene encodes complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. This cluster includes several genes involved in regulation of the immune reaction. Polymorphisms in this gene are associated with a reduced risk of age-related macular degeneration. The polyadenylation site of this gene is 421 bp from the 5' end of the gene for complement component 2. [provided by RefSeq, Jul 2008] | |
|---|---|---|
| DyLight 350 | DyLight™ 350 has an excitation peak of 353 nm and an emission peak of 432 nm. It is spectrally similar to Alexa Fluor™ 350, iFluor® 350, AMCA, and Thioflavin T. DyLight™ 350 is most commonly used in flow cytometery and fluorescence microscopy applications. |
Citations
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