FluoroFinder

	Supplier
	Catalog #:	NBP2-23549AF647 (View supplier product page)
	Size	100 μl
	Price	$329.00
	Antigen	Complement C2
	Clone	5C3
	Host	Mouse
	Isotype	IgG2a κ
	Conjugate	Alexa Fluor 647
	Target Species	Human
	Applications	WB, ELISA, IHC
	Description	Optimal dilution of this antibody should be experimentally determined.

	Complement C2	Component C2 is a serum glycoprotein that functions as part of the classical pathway of the complement system. Activated C1 cleaves C2 into C2a and C2b. The serine proteinase C2a then combines with complement factor 4b to create the C3 or C5 convertase. Deficiency of C2 has been reported to associated with certain autoimmune diseases and SNPs in this gene have been associated with altered susceptibility to age-related macular degeneration. This gene localizes within the class III region of the MHC on the short arm of chromosome 6. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described in publications but their full-length sequence has not been determined.[provided by RefSeq, Mar 2009]
	Alexa Fluor 647	Alexa Fluor™ 647 (AF647, Alexa 647) has an excitation peak at 650 nm and an emission peak at 665 nm, and is spectrally similar to Cy®5 (GE Healthcare), iFluor® 647 (ATT Bioquest), and DyLight™ 650 (Thermo Fisher Scientific). Alexa 647 is commonly used for flow cytometry, microscopy, super-resolution microscopy applications. It is very bright, photostable, and pH insensitive, all of which contribute to sensitive detection while using this dye.

	Additional Sources

Complement C2 Monoclonal / Alexa Fluor 647 / 5C3