Protein Disulfide Isomerase Monoclonal / NL 637 / 537331
Protein Disulfide Isomerase Monoclonal / NL 637 / 537331
Product Details
| Supplier | ||
|---|---|---|
| Catalog #: | NL4236V (View supplier product page) | |
| Size | 500 μl | |
| Price | $355.00 | |
| Antigen | Protein Disulfide Isomerase | |
| Clone | 537331 | |
| Host | Mouse | |
| Isotype | IgG2a | |
| Conjugate | NL 637 | |
| Target Species | Human | |
| Applications | ICC |
About Protein Disulfide Isomerase and NL 637
| Protein Disulfide Isomerase | This gene encodes the beta subunit of prolyl 4-hydroxylase, a highly abundant multifunctional enzyme that belongs to the protein disulfide isomerase family. When present as a tetramer consisting of two alpha and two beta subunits, this enzyme is involved in hydroxylation of prolyl residues in preprocollagen. This enzyme is also a disulfide isomerase containing two thioredoxin domains that catalyze the formation, breakage and rearrangement of disulfide bonds. Other known functions include its ability to act as a chaperone that inhibits aggregation of misfolded proteins in a concentration-dependent manner, its ability to bind thyroid hormone, its role in both the influx and efflux of S-nitrosothiol-bound nitric oxide, and its function as a subunit of the microsomal triglyceride transfer protein complex. [provided by RefSeq, Jul 2008] | |
|---|---|---|
| NL 637 | NL 637 from Bio-Techne is a fluorophore with an excitation peak at 637 nm and an emission peak at 658 nm. It can be used in fluorescence microscopy. |
Citations
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