Perforin / DyLight 680 / 9G33
Perforin / DyLight 680 / 9G33
Product Details
| Supplier | ||
|---|---|---|
| Catalog #: | NBP2-21953FR (View supplier product page) | |
| Size | 100 μl | |
| Price | $379.00 | |
| Antigen | Perforin | |
| Clone | 9G33 | |
| Host | Rat | |
| Isotype | IgG2 | |
| Conjugate | DyLight 680 | |
| Target Species | Mouse | |
| Applications | WB |
About Perforin and DyLight 680
| Perforin | This gene encodes a protein with structural similarities to complement component C9 that is important in immunity. This protein forms membrane pores that allow the release of granzymes and subsequent cytolysis of target cells. Whether pore formation occurs in the plasma membrane of target cells or in an endosomal membrane inside target cells is subject to debate. Mutations in this gene are associated with a variety of human disease including diabetes, multiple sclerosis, lymphomas, autoimmune lymphoproliferative syndrome (ALPS), aplastic anemia, and familial hemophagocytic lymphohistiocytosis type 2 (FHL2), a rare and lethal autosomal recessive disorder of early childhood. [provided by RefSeq, Aug 2017] | |
|---|---|---|
| DyLight 680 | DyLight™ 680 has an excitation peak at 692 nm and an emission peak at 712 nm, and is spectrally similar to Alexa Fluor™ 680 and Cy5.5. DyLight™ 680 is most commonly used in flow cytometery and fluorescence microscopy applications. |
Citations
| Additional Sources |
|
|---|
