Perforin / DyLight 350 / 9G33
Perforin / DyLight 350 / 9G33
Product Details
| Supplier | ||
|---|---|---|
| Catalog #: | NBP2-21953UV (View supplier product page) | |
| Size | 100 μl | |
| Price | $379.00 | |
| Antigen | Perforin | |
| Clone | 9G33 | |
| Host | Rat | |
| Isotype | IgG2 | |
| Conjugate | DyLight 350 | |
| Target Species | Mouse | |
| Applications | WB |
About Perforin and DyLight 350
| Perforin | This gene encodes a protein with structural similarities to complement component C9 that is important in immunity. This protein forms membrane pores that allow the release of granzymes and subsequent cytolysis of target cells. Whether pore formation occurs in the plasma membrane of target cells or in an endosomal membrane inside target cells is subject to debate. Mutations in this gene are associated with a variety of human disease including diabetes, multiple sclerosis, lymphomas, autoimmune lymphoproliferative syndrome (ALPS), aplastic anemia, and familial hemophagocytic lymphohistiocytosis type 2 (FHL2), a rare and lethal autosomal recessive disorder of early childhood. [provided by RefSeq, Aug 2017] | |
|---|---|---|
| DyLight 350 | DyLight™ 350 has an excitation peak of 353 nm and an emission peak of 432 nm. It is spectrally similar to Alexa Fluor™ 350, iFluor® 350, AMCA, and Thioflavin T. DyLight™ 350 is most commonly used in flow cytometery and fluorescence microscopy applications. |
Citations
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