Urokinase / DyLight 755 / MM0596-8G26
Urokinase / DyLight 755 / MM0596-8G26
Product Details
| Supplier | ||
|---|---|---|
| Catalog #: | NBP2-11990IR (View supplier product page) | |
| Size | 100 μl | |
| Price | $429.00 | |
| Antigen | Urokinase | |
| Clone | MM0596-8G26 | |
| Host | Mouse | |
| Isotype | IgG1 | |
| Conjugate | DyLight 755 | |
| Target Species | Human | |
| Applications | WB |
About Urokinase and DyLight 755
| Urokinase | This gene encodes a secreted serine protease that converts plasminogen to plasmin. The encoded preproprotein is proteolytically processed to generate A and B polypeptide chains. These chains associate via a single disulfide bond to form the catalytically inactive high molecular weight urokinase-type plasminogen activator (HMW-uPA). HMW-uPA can be further processed into the catalytically active low molecular weight urokinase-type plasminogen activator (LMW-uPA). This low molecular weight form does not bind to the urokinase-type plasminogen activator receptor. Mutations in this gene may be associated with Quebec platelet disorder and late-onset Alzheimer's disease. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016] | |
|---|---|---|
| DyLight 755 | DyLight™ 755 has an excitation peak of 754 nm and an emission peak of 776 nm and is spectrally similar to Alexa Fluor™ 750. DyLight™ 755 is most commonly used in fluorescence micrscopy. |
Citations
| Additional Sources |
|
|---|
