CD263 Monoclonal / DyLight 405 / MM0578-4H10
CD263 Monoclonal / DyLight 405 / MM0578-4H10
Product Details
| Supplier | ||
|---|---|---|
| Catalog #: | NBP2-11930V (View supplier product page) | |
| Size | 100 μl | |
| Price | $429.00 | |
| Antigen | CD263 | |
| Clone | MM0578-4H10 | |
| Host | Mouse | |
| Isotype | IgG1 | |
| Conjugate | DyLight 405 | |
| Target Species | Human | |
| Applications | WB, IHC-P, IHC |
About CD263 and DyLight 405
| CD263 | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL. [provided by RefSeq, Jul 2008] | |
|---|---|---|
| DyLight 405 | DyLight™ 405 has an excitation peak at 400 nm and an emission peak at 420 nm and is spectrally similar to Alexa Fluor™ 405 and Cascade Blue. DyLight™ 405 is most commonly used in flow cytometery and fluorescence microscopy applications. |
Citations
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