FluoroFinder

	Supplier
	Catalog #:	NBP2-37425R (View supplier product page)
	Size	100 μl
	Price	$399.00
	Antigen	Prosurfactant Protein C
	Clone	5E6A9
	Host	Mouse
	Isotype	IgG1
	Conjugate	DyLight 550
	Target Species	Human
	Applications	WB, ELISA

	Prosurfactant Protein C	This gene encodes the pulmonary-associated surfactant protein C (SPC), an extremely hydrophobic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90% lipids and 10% proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 2, also called pulmonary alveolar proteinosis due to surfactant protein C deficiency, and are associated with interstitial lung disease in older infants, children, and adults. Alternatively spliced transcript variants encoding different protein isoforms have been identified.[provided by RefSeq, Feb 2010]
	DyLight 550	DyLight™ 550 has an excitation peak at 562 nm and an emission peak at 576 nm and is spectrally similar to Alexa Fluor™ 546, Alexa Fluor™ 555, Cy3 and TRITC. DyLight™ 550 is most commonly used in flow cytometery and fluorescence microscopy applications.

	Additional Sources

Prosurfactant Protein C / DyLight 550 / 5E6A9