PTP4A2 / DyLight 405 / 5B6F4
PTP4A2 / DyLight 405 / 5B6F4
Product Details
| Supplier | ||
|---|---|---|
| Catalog #: | NBP2-37315V (View supplier product page) | |
| Size | 100 μl | |
| Price | $399.00 | |
| Antigen | PTP4A2 | |
| Clone | 5B6F4 | |
| Host | Mouse | |
| Isotype | IgG2b | |
| Conjugate | DyLight 405 | |
| Target Species | Human | |
| Applications | WB, ELISA |
About PTP4A2 and DyLight 405
| PTP4A2 | The protein encoded by this gene belongs to a small class of the protein tyrosine phosphatase (PTP) family. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. PTPs in this class contain a protein tyrosine phosphatase catalytic domain and a characteristic C-terminal prenylation motif. This PTP has been shown to primarily associate with plasmic and endosomal membrane through its C-terminal prenylation. This PTP was found to interact with the beta-subunit of Rab geranylgeranyltransferase II (beta GGT II), and thus may function as a regulator of GGT II activity. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which suggested its role in tumorigenesis. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 11, 12 and 17. [provided by RefSeq, Aug 2010] | |
|---|---|---|
| DyLight 405 | DyLight™ 405 has an excitation peak at 400 nm and an emission peak at 420 nm and is spectrally similar to Alexa Fluor™ 405 and Cascade Blue. DyLight™ 405 is most commonly used in flow cytometery and fluorescence microscopy applications. |
Citations
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