FluoroFinder

	Supplier
	Catalog #:	NBP2-36790V (View supplier product page)
	Size	100 μl
	Price	$479.00
	Antigen	Lck
	Clone	MM0796-24Z21
	Host	Mouse
	Isotype	IgG2
	Conjugate	DyLight 405
	Target Species	Human
	Applications	WB, FC

	Lck	This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants encoding different isoforms have been described. [provided by RefSeq, Aug 2016]
	DyLight 405	DyLight™ 405 has an excitation peak at 400 nm and an emission peak at 420 nm and is spectrally similar to Alexa Fluor™ 405 and Cascade Blue. DyLight™ 405 is most commonly used in flow cytometery and fluorescence microscopy applications.

	Additional Sources

Lck / DyLight 405 / MM0796-24Z21