SSRP1 / DyLight 350 / 10D1
SSRP1 / DyLight 350 / 10D1
Product Details
| Supplier | ||
|---|---|---|
| Catalog #: | NB100-78323UV (View supplier product page) | |
| Size | 100 μl | |
| Price | $369.00 | |
| Antigen | SSRP1 | |
| Clone | 10D1 | |
| Host | Mouse | |
| Isotype | IgG2b κ | |
| Conjugate | DyLight 350 | |
| Target Species | Human | |
| Applications | ICC/IF, WB | |
| Description | Protein A or G purified |
About SSRP1 and DyLight 350
| SSRP1 | The protein encoded by this gene is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. This protein also functions as a co-activator of the transcriptional activator p63. An alternatively spliced transcript variant of this gene has been described, but its full-length nature is not known. [provided by RefSeq, Jul 2008] | |
|---|---|---|
| DyLight 350 | DyLight™ 350 has an excitation peak of 353 nm and an emission peak of 432 nm. It is spectrally similar to Alexa Fluor™ 350, iFluor® 350, AMCA, and Thioflavin T. DyLight™ 350 is most commonly used in flow cytometery and fluorescence microscopy applications. |
Citations
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