FluoroFinder

	Supplier
	Catalog #:	NBP1-28604C (View supplier product page)
	Size	100 μl
	Price	$399.00
	Antigen	MMP-1
	Clone	SB12e
	Host	Mouse
	Isotype	IgG2b κ
	Conjugate	DyLight 650
	Target Species	Human
	Applications	IHC-P, ICC/IF, WB, ELISA, IHC-Fr

	MMP-1	This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down the interstitial collagens, including types I, II, and III. The gene is part of a cluster of MMP genes on chromosome 11. Mutations in this gene are associated with chronic obstructive pulmonary disease (COPD). Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016]
	DyLight 650	DyLight™ 650 is a red-emitting fluorophore that excited by the 640 nm laser and collected using a 670/30 nm bandpass filter. DyLight™ 650 has an excitation peak at 652 nm and an emission peak at 672 nm, and is spectrally similar to Alexa Fluor™ 647 and Cy5. DyLight™ 650 is most commonly used in flow cytometery and fluorescence microscopy applications.

	Additional Sources

MMP-1 / DyLight 650 / SB12e