IDO1 / DyLight 680 / mIDO-48
IDO1 / DyLight 680 / mIDO-48
Product Details
| Supplier | ||
|---|---|---|
| Catalog #: | NB100-77696FR (View supplier product page) | |
| Size | 100 μl | |
| Price | $369.00 | |
| Antigen | IDO1 | |
| Clone | mIDO-48 | |
| Host | Rat | |
| Isotype | IgG2b κ | |
| Conjugate | DyLight 680 | |
| Target Species | Human, Mouse | |
| Applications | IHC-P, WB, IHC-Fr |
About IDO1 and DyLight 680
| IDO1 | This gene encodes indoleamine 2,3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.[provided by RefSeq, Feb 2011] | |
|---|---|---|
| DyLight 680 | DyLight™ 680 has an excitation peak at 692 nm and an emission peak at 712 nm, and is spectrally similar to Alexa Fluor™ 680 and Cy5.5. DyLight™ 680 is most commonly used in flow cytometery and fluorescence microscopy applications. |
Citations
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