4EBP1 / DyLight 405 / 11G12C11
4EBP1 / DyLight 405 / 11G12C11
Product Details
| Supplier | ||
|---|---|---|
| Catalog #: | NBP1-47366V (View supplier product page) | |
| Size | 100 μl | |
| Price | $349.00 | |
| Antigen | 4EBP1 | |
| Clone | 11G12C11 | |
| Host | Mouse | |
| Isotype | IgG1 | |
| Conjugate | DyLight 405 | |
| Target Species | Human | |
| Applications | IHC-P, WB, ELISA |
About 4EBP1 and DyLight 405
| 4EBP1 | This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. [provided by RefSeq, Jul 2008] | |
|---|---|---|
| DyLight 405 | DyLight™ 405 has an excitation peak at 400 nm and an emission peak at 420 nm and is spectrally similar to Alexa Fluor™ 405 and Cascade Blue. DyLight™ 405 is most commonly used in flow cytometery and fluorescence microscopy applications. |
Citations
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