FluoroFinder

	Supplier
	Catalog #:	NBP2-42635V (View supplier product page)
	Size	100 μl
	Price	$369.00
	Antigen	CD179b
	Clone	1G4
	Host	Mouse
	Isotype	IgG1 κ
	Conjugate	DyLight 405
	Target Species	Human
	Applications	WB, ELISA
	Description	Protein A purified

	CD179b	The preB cell receptor is found on the surface of proB and preB cells, where it is involved in transduction of signals for cellular proliferation, differentiation from the proB cell to the preB cell stage, allelic exclusion at the Ig heavy chain gene locus, and promotion of Ig light chain gene rearrangements. The preB cell receptor is composed of a membrane-bound Ig mu heavy chain in association with a heterodimeric surrogate light chain. This gene encodes one of the surrogate light chain subunits and is a member of the immunoglobulin gene superfamily. This gene does not undergo rearrangement. Mutations in this gene can result in B cell deficiency and agammaglobulinemia, an autosomal recessive disease in which few or no gamma globulins or antibodies are made. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
	DyLight 405	DyLight™ 405 has an excitation peak at 400 nm and an emission peak at 420 nm and is spectrally similar to Alexa Fluor™ 405 and Cascade Blue. DyLight™ 405 is most commonly used in flow cytometery and fluorescence microscopy applications.

	Additional Sources

CD179b / DyLight 405 / 1G4