Sphingosine Kinase 2 / Alexa Fluor 647 / 3C8D3

Product Details
Supplier
Catalog #: NBP2-52566AF647 (View supplier product page)
Size 100 μl
Price $429.00
Antigen Sphingosine Kinase 2
Clone 3C8D3
Host Mouse
Isotype IgG1
Conjugate Alexa Fluor 647
Target Species Human
Applications WB, ELISA, FC
About Sphingosine Kinase 2 and Alexa Fluor 647
Sphingosine Kinase 2 This gene encodes one of two sphingosine kinase isozymes that catalyze the phosphorylation of sphingosine into sphingosine 1-phosphate. Sphingosine 1-phosphate mediates many cellular processes including migration, proliferation and apoptosis, and also plays a role in several types of cancer by promoting angiogenesis and tumorigenesis. The encoded protein may play a role in breast cancer proliferation and chemoresistance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011]
Alexa Fluor 647 Alexa Fluor™ 647 (AF647, Alexa 647) has an excitation peak at 650 nm and an emission peak at 665 nm, and is spectrally similar to Cy®5 (GE Healthcare), iFluor® 647 (ATT Bioquest), and DyLight™ 650 (Thermo Fisher Scientific). Alexa 647 is commonly used for flow cytometry, microscopy, super-resolution microscopy applications. It is very bright, photostable, and pH insensitive, all of which contribute to sensitive detection while using this dye.
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Alexa Fluor 647 Excitation and Emission Spectra