Caspase 7 / Alexa Fluor 405 / 4D10B2

Product Details
Supplier
Catalog #: NBP2-52430AF405 (View supplier product page)
Size 100 μl
Price $429.00
Antigen Caspase 7
Clone 4D10B2
Host Mouse
Isotype IgG
Conjugate Alexa Fluor 405
Target Species Human
Applications WB, ELISA, FC
About Caspase 7 and Alexa Fluor 405
Caspase 7 This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of the encoded protein is cleaved by caspase 3 and 10, is activated upon cell death stimuli and induces apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2012]
Alexa Fluor 405 Alexa Fluor™ 405 (AF405, Alexa 405) has an excitation peak at 401 nm and an emission peak at 421 nm and is similar in size, brightness and application to ABflo 405® (ABclonal) and Cascade Blue® (ThermoFisher Scientific). Alexa 405 is commonly used in flow cytometery and fluorescence microscopy applications.
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Alexa Fluor 405 Excitation and Emission Spectra