AGR2 / DyLight 650 / Polyclonal
AGR2 / DyLight 650 / Polyclonal
Product Details
| Supplier | ||
|---|---|---|
| Catalog #: | NBP2-27392C (View supplier product page) | |
| Size | 100 μl | |
| Price | $409.00 | |
| Antigen | AGR2 | |
| Clone | Polyclonal | |
| Host | Rabbit | |
| Isotype | IgG | |
| Conjugate | DyLight 650 | |
| Target Species | Human, Mouse | |
| Applications | WB, IHC-Fr, IHC-P | |
| Description | Protein G purified |
About AGR2 and DyLight 650
| AGR2 | This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, and a C-terminal ER-retention sequence. This protein plays a role in cell migration, cellular transformation and metastasis and is as a p53 inhibitor. As an ER-localized molecular chaperone, it plays a role in the folding, trafficking, and assembly of cysteine-rich transmembrane receptors and the cysteine-rich intestinal gylcoprotein mucin. This gene has been implicated in inflammatory bowel disease and cancer progression. [provided by RefSeq, Mar 2017] | |
|---|---|---|
| DyLight 650 | DyLight™ 650 is a red-emitting fluorophore that excited by the 640 nm laser and collected using a 670/30 nm bandpass filter. DyLight™ 650 has an excitation peak at 652 nm and an emission peak at 672 nm, and is spectrally similar to Alexa Fluor™ 647 and Cy5. DyLight™ 650 is most commonly used in flow cytometery and fluorescence microscopy applications. |
Citations
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