MMP-3 / DyLight 350 / SB14d
MMP-3 / DyLight 350 / SB14d
Product Details
Supplier | ||
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Catalog #: | NBP1-28615UV (View supplier product page) | |
Size | 100 μl | |
Price | $379.00 | |
Antigen | MMP-3 | |
Clone | SB14d | |
Host | Mouse | |
Isotype | IgG2a | |
Conjugate | DyLight 350 | |
Target Species | Human | |
Applications | IHC-P, ELISA, IHC-Fr |
About MMP-3 and DyLight 350
MMP-3 | Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades fibronectin, laminin, collagens III, IV, IX, and X, and cartilage proteoglycans. The enzyme is thought to be involved in wound repair, progression of atherosclerosis, and tumor initiation. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq, Jul 2008] | |
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DyLight 350 | DyLight™ 350 has an excitation peak of 353 nm and an emission peak of 432 nm. It is spectrally similar to Alexa Fluor™ 350, iFluor® 350, AMCA, and Thioflavin T. DyLight™ 350 is most commonly used in flow cytometery and fluorescence microscopy applications. |