14-3-3 epsilon / DyLight 350 / 5A5
14-3-3 epsilon / DyLight 350 / 5A5
Product Details
Supplier | ||
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Catalog #: | NBP1-22960UV (View supplier product page) | |
Size | 100 μl | |
Price | $349.00 | |
Antigen | 14-3-3 epsilon | |
Clone | 5A5 | |
Host | Mouse | |
Isotype | IgG2a κ | |
Conjugate | DyLight 350 | |
Target Species | Human | |
Applications | WB, ELISA |
About 14-3-3 epsilon and DyLight 350
14-3-3 epsilon | This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Two transcript variants, one protein-coding and the other non-protein-coding, have been found for this gene. [provided by RefSeq, Aug 2008] | |
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DyLight 350 | DyLight™ 350 has an excitation peak of 353 nm and an emission peak of 432 nm. It is spectrally similar to Alexa Fluor™ 350, iFluor® 350, AMCA, and Thioflavin T. DyLight™ 350 is most commonly used in flow cytometery and fluorescence microscopy applications. |