FluoroFinder

	Supplier
	Catalog #:	NB100-78489V (View supplier product page)
	Size	100 μl
	Price	$369.00
	Antigen	Elongin B
	Clone	10C4
	Host	Mouse
	Isotype	IgG1 κ
	Conjugate	DyLight 405
	Target Species	Human
	Applications	WB
	Description	Protein G purified

	Elongin B	This gene encodes the protein elongin B, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene. Pseudogenes have been identified on chromosomes 11 and 13. [provided by RefSeq, Aug 2008]
	DyLight 405	DyLight™ 405 has an excitation peak at 400 nm and an emission peak at 420 nm and is spectrally similar to Alexa Fluor™ 405 and Cascade Blue. DyLight™ 405 is most commonly used in flow cytometery and fluorescence microscopy applications.

	Additional Sources

Elongin B / DyLight 405 / 10C4