IL-6 / DyLight 488 / MQ2-39C3
IL-6 / DyLight 488 / MQ2-39C3
Product Details
| Supplier | ||
|---|---|---|
| Catalog #: | NBP2-33048G (View supplier product page) | |
| Size | 500 μl | |
| Price | $369.00 | |
| Antigen | IL-6 | |
| Clone | MQ2-39C3 | |
| Host | Rat | |
| Isotype | IgG κ | |
| Conjugate | DyLight 488 | |
| Target Species | Human, Monkey, Rhesus macaque | |
| Applications | WB, ELISA, FC | |
| Description | Protein A or G purified |
About IL-6 and DyLight 488
| IL-6 | This gene encodes a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been identified in this gene. A pseudogene of this gene is found on chromosome 9. [provided by RefSeq, Aug 2020] | |
|---|---|---|
| DyLight 488 | DyLight™ 488 has an excitation peak at 493 nm and an emission peak at 518 nm and is spectrally similar to Alexa Fluor™ 488, fluorescein and FITC. DyLight™ 488 is most commonly used in flow cytometery, and fluorescence microscopy applications. |
Citations
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