PPM1A / APC / p6c7
PPM1A / APC / p6c7
Product Details
| Supplier | ||
|---|---|---|
| Catalog #: | NBP1-04333APC (View supplier product page) | |
| Size | 100 μl | |
| Price | $369.00 | |
| Antigen | PPM1A | |
| Clone | p6c7 | |
| Host | Mouse | |
| Isotype | IgG2b κ | |
| Conjugate | APC | |
| Target Species | Human, Mouse | |
| Applications | WB, ELISA | |
| Description | Protein G purified |
About PPM1A and APC
| PPM1A | The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase dephosphorylates, and negatively regulates the activities of, MAP kinases and MAP kinase kinases. It has been shown to inhibit the activation of p38 and JNK kinase cascades induced by environmental stresses. This phosphatase can also dephosphorylate cyclin-dependent kinases, and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to activate the expression of the tumor suppressor gene TP53/p53, which leads to G2/M cell cycle arrest and apoptosis. Three alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008] | |
|---|---|---|
| APC | Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm. |
Citations
| Additional Sources |
|
|---|
