CD263 / DyLight 350 / TRAIL-R3-02
CD263 / DyLight 350 / TRAIL-R3-02
Product Details
| Supplier | ||
|---|---|---|
| Catalog #: | NB110-68802UV (View supplier product page) | |
| Size | 100 μl | |
| Price | $379.00 | |
| Antigen | CD263 | |
| Clone | TRAIL-R3-02 | |
| Host | Mouse | |
| Isotype | IgG1 | |
| Conjugate | DyLight 350 | |
| Target Species | Human | |
| Applications | FC |
About CD263 and DyLight 350
| CD263 | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL. [provided by RefSeq, Jul 2008] | |
|---|---|---|
| DyLight 350 | DyLight™ 350 has an excitation peak of 353 nm and an emission peak of 432 nm. It is spectrally similar to Alexa Fluor™ 350, iFluor® 350, AMCA, and Thioflavin T. DyLight™ 350 is most commonly used in flow cytometery and fluorescence microscopy applications. |
Citations
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