Epo / Alexa Fluor 488 / BGN/6B8
Epo / Alexa Fluor 488 / BGN/6B8
Product Details
Supplier | ||
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Catalog #: | NB100-62547AF488 (View supplier product page) | |
Size | 100 μl | |
Price | $369.00 | |
Antigen | Epo | |
Clone | BGN/6B8 | |
Host | Mouse | |
Isotype | IgG1 | |
Conjugate | Alexa Fluor 488 | |
Target Species | Human | |
Applications | ELISA | |
Description | Protein A or G purified |
About Epo and Alexa Fluor 488
Epo | This gene encodes a secreted, glycosylated cytokine composed of four alpha helical bundles. The encoded protein is mainly synthesized in the kidney, secreted into the blood plasma, and binds to the erythropoietin receptor to promote red blood cell production, or erythropoiesis, in the bone marrow. Expression of this gene is upregulated under hypoxic conditions, in turn leading to increased erythropoiesis and enhanced oxygen-carrying capacity of the blood. Expression of this gene has also been observed in brain and in the eye, and elevated expression levels have been observed in diabetic retinopathy and ocular hypertension. Recombinant forms of the encoded protein exhibit neuroprotective activity against a variety of potential brain injuries, as well as antiapoptotic functions in several tissue types, and have been used in the treatment of anemia and to enhance the efficacy of cancer therapies. [provided by RefSeq, Aug 2017] | |
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Alexa Fluor 488 | Alexa Fluor™ 488 (AF488, Alexa 488) has an excitation peak at 488 nm and an emission peak at 496 nm, and is considered a high-performance alternative to FITC. Alexa 488 is one of the most popular Alexa Fluor™ dyes and is widely used in Fluorescence Microscopy, flow cytometry, and for staining low expression markers. It is bright, highly photostable, resistant to pH changes, and less susceptible to photobleaching. Alexa 488 and is similar in size, brightness and application to DyLight™ 488, iFluor® 488 and CF®488A. |