FluoroFinder

	Supplier
	Catalog #:	NB110-60506V3 (View supplier product page)
	Size	100 μl
	Price	$369.00
	Antigen	MAPK1
	Clone	4C11
	Host	Mouse
	Isotype	IgG2a
	Conjugate	DyLight 405LS
	Target Species	Human, Monkey, Mouse
	Applications	WB, ELISA, IHC-Fr, IHC-P, ICC/IF
	Description	Protein A purified

	MAPK1	This gene encodes a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. One study also suggests that this protein acts as a transcriptional repressor independent of its kinase activity. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene. [provided by RefSeq, Jan 2014]

	Additional Sources

MAPK1 / DyLight 405LS / 4C11