FluoroFinder

	Supplier
	Catalog #:	NBP2-22533V3 (View supplier product page)
	Size	200 μl
	Price	$369.00
	Antigen	CXCL11
	Clone	10C6
	Host	Mouse
	Isotype	IgG1
	Conjugate	DyLight 405LS
	Target Species	Human
	Applications	WB, ELISA
	Description	Protein G purified

	CXCL11	Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC. This antimicrobial gene is a CXC member of the chemokine superfamily. Its encoded protein induces a chemotactic response in activated T-cells and is the dominant ligand for CXC receptor-3. The gene encoding this protein contains 4 exons and at least three polyadenylation signals which might reflect cell-specific regulation of expression. IFN-gamma is a potent inducer of transcription of this gene. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2014]

	Additional Sources

CXCL11 / DyLight 405LS / 10C6