ChT1 / DyLight 350 / CT1
ChT1 / DyLight 350 / CT1
Product Details
Supplier | ||
---|---|---|
Catalog #: | NBP1-28355UV (View supplier product page) | |
Size | 500 μl | |
Price | $459.00 | |
Antigen | ChT1 | |
Clone | CT1 | |
Host | Mouse | |
Isotype | IgG1 κ | |
Conjugate | DyLight 350 | |
Target Species | Avian, Chicken | |
Applications | FC | |
Description | Protein A or G purified |
About ChT1 and DyLight 350
ChT1 | This gene encodes a sodium ion- and chloride ion-dependent high-affinity transporter that mediates choline uptake for acetylcholine synthesis in cholinergic neurons. The protein transports choline from the extracellular space into presynaptic terminals for synthesis into acetylcholine. Increased choline uptake results from increased density of this protein in synaptosomal plasma membranes in response to depolarization of cholinergic terminals. Dysfunction of cholinergic signaling has been implicated in various disorders including depression, attention-deficit disorder, and schizophrenia. An allelic variant of this gene is associated with autosomal dominant distal hereditary motor neuronopathy type VIIA. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015] | |
---|---|---|
DyLight 350 | DyLight™ 350 has an excitation peak of 353 nm and an emission peak of 432 nm. It is spectrally similar to Alexa Fluor™ 350, iFluor® 350, AMCA, and Thioflavin T. DyLight™ 350 is most commonly used in flow cytometery and fluorescence microscopy applications. |