ChT1 / DyLight 755 / CT1

Product Details
Supplier
Catalog #: NBP1-28355IR (View supplier product page)
Size 500 μl
Price $459.00
Antigen ChT1
Clone CT1
Host Mouse
Isotype IgG1 κ
Conjugate DyLight 755
Target Species Avian, Chicken
Applications FC
Description Protein A or G purified
About ChT1 and DyLight 755
ChT1 This gene encodes a sodium ion- and chloride ion-dependent high-affinity transporter that mediates choline uptake for acetylcholine synthesis in cholinergic neurons. The protein transports choline from the extracellular space into presynaptic terminals for synthesis into acetylcholine. Increased choline uptake results from increased density of this protein in synaptosomal plasma membranes in response to depolarization of cholinergic terminals. Dysfunction of cholinergic signaling has been implicated in various disorders including depression, attention-deficit disorder, and schizophrenia. An allelic variant of this gene is associated with autosomal dominant distal hereditary motor neuronopathy type VIIA. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]
DyLight 755 DyLight™ 755 has an excitation peak of 754 nm and an emission peak of 776 nm and is spectrally similar to Alexa Fluor™ 750. DyLight™ 755 is most commonly used in fluorescence micrscopy.
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DyLight 755 Excitation and Emission Spectra