CD8a / DyLight 550 / RAVB3
CD8a / DyLight 550 / RAVB3
Product Details
Supplier | ||
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Catalog #: | NBP1-47335R (View supplier product page) | |
Size | 100 μl | |
Price | $399.00 | |
Antigen | CD8a | |
Clone | RAVB3 | |
Host | Mouse | |
Isotype | IgG1 | |
Conjugate | DyLight 550 | |
Target Species | Human | |
Applications | ELISA, FC | |
Description | Protein A or G purified |
About CD8a and DyLight 550
CD8a | The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. The major protein isoforms of this gene differ by the presence or absence of a transmembrane domain and thus differ in being a membrane-anchored or secreted protein. [provided by RefSeq, May 2020] | |
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DyLight 550 | DyLight™ 550 has an excitation peak at 562 nm and an emission peak at 576 nm and is spectrally similar to Alexa Fluor™ 546, Alexa Fluor™ 555, Cy3 and TRITC. DyLight™ 550 is most commonly used in flow cytometery and fluorescence microscopy applications. |