CD45 / DyLight 680 / 2H12
CD45 / DyLight 680 / 2H12
Product Details
| Supplier | ||
|---|---|---|
| Catalog #: | NBP1-04274FR (View supplier product page) | |
| Size | 100 μl | |
| Price | $369.00 | |
| Antigen | CD45 | |
| Clone | 2H12 | |
| Host | Mouse | |
| Isotype | IgG2b | |
| Conjugate | DyLight 680 | |
| Target Species | Human | |
| Applications | ELISA, FC | |
| Description | Protein G purified |
About CD45 and DyLight 680
| CD45 | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jun 2012] | |
|---|---|---|
| DyLight 680 | DyLight™ 680 has an excitation peak at 692 nm and an emission peak at 712 nm, and is spectrally similar to Alexa Fluor™ 680 and Cy5.5. DyLight™ 680 is most commonly used in flow cytometery and fluorescence microscopy applications. |
Citations
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