CD38 / Alexa Fluor 405 / NIMR-5
CD38 / Alexa Fluor 405 / NIMR-5
Product Details
Supplier | ||
---|---|---|
Catalog #: | NBP1-27951AF405 (View supplier product page) | |
Size | 500 μl | |
Price | $449.00 | |
Antigen | CD38 | |
Clone | NIMR-5 | |
Host | Rat | |
Isotype | IgG2a κ | |
Conjugate | Alexa Fluor 405 | |
Target Species | Mouse | |
Applications | FC, IHC-Fr | |
Description | Protein A or G purified |
About CD38 and Alexa Fluor 405
CD38 | The protein encoded by this gene is a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5'-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Crystal structure analysis demonstrates that the functional molecule is a dimer, with the central portion containing the catalytic site. It is used as a prognostic marker for patients with chronic lymphocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015] | |
---|---|---|
Alexa Fluor 405 | Alexa Fluor™ 405 (AF405, Alexa 405) has an excitation peak at 401 nm and an emission peak at 421 nm and is similar in size, brightness and application to ABflo 405® (ABclonal) and Cascade Blue® (ThermoFisher Scientific). Alexa 405 is commonly used in flow cytometery and fluorescence microscopy applications. |