CCR6 / DyLight 488 / 53103.111
CCR6 / DyLight 488 / 53103.111
Product Details
Supplier | ||
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Catalog #: | NB120-10398G (View supplier product page) | |
Size | 100 μl | |
Price | $349.00 | |
Antigen | CCR6 | |
Clone | 53103.111 | |
Host | Mouse | |
Isotype | IgG2b | |
Conjugate | DyLight 488 | |
Target Species | Human | |
Applications | FC |
About CCR6 and DyLight 488
CCR6 | This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene. [provided by RefSeq, Jul 2008] | |
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DyLight 488 | DyLight™ 488 has an excitation peak at 493 nm and an emission peak at 518 nm and is spectrally similar to Alexa Fluor™ 488, fluorescein and FITC. DyLight™ 488 is most commonly used in flow cytometery, and fluorescence microscopy applications. |