CD45 / DyLight 755 / C11
CD45 / DyLight 755 / C11
Product Details
| Supplier | ||
|---|---|---|
| Catalog #: | NB100-2657IR (View supplier product page) | |
| Size | 100 μl | |
| Price | $329.00 | |
| Antigen | CD45 | |
| Clone | C11 | |
| Host | Mouse | |
| Isotype | IgG2a | |
| Conjugate | DyLight 755 | |
| Target Species | Human | |
| Applications | IHC-Fr | |
| Description | Protein A or G purified |
About CD45 and DyLight 755
| CD45 | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitosis, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus is classified as a receptor type PTP. This PTP has been shown to be an essential regulator of T- and B-cell antigen receptor signaling. It functions through either direct interaction with components of the antigen receptor complexes, or by activating various Src family kinases required for the antigen receptor signaling. This PTP also suppresses JAK kinases, and thus functions as a regulator of cytokine receptor signaling. Alternatively spliced transcripts variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jun 2012] | |
|---|---|---|
| DyLight 755 | DyLight™ 755 has an excitation peak of 754 nm and an emission peak of 776 nm and is spectrally similar to Alexa Fluor™ 750. DyLight™ 755 is most commonly used in fluorescence micrscopy. |
Citations
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